CAS NO. |
Products Name |
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896720-20-0 |
VX-11e |
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VX-11e is a potent, selective, and orally bioavailable inhibitor of ERK (Extracellular Signal-RegulatedKinase). Antitumor agents |
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1146963-51-0 |
J147 |
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J-147 is a broad spectrum neuroprotective phenyl hydrazide compound(EC50=60-115 nM) with significant neurotrophic properties related to the induction of brain-derived neurotrophic factor (BDNF). |
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1598383-40-4 |
EPZ011989 |
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EPZ011989 is a potent, selective orally bioavailable EZH2 inhibitor with Ki < 3 nM for EZH2 wt and EZH2 Y646; 15-fold selectivity over EZH1 and >3000-fold selectivity over other HMTase. |
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297730-17-7 |
AVN944 |
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AVN-944(VX-944) is a selective, noncompetitive inhibitor of the enzyme directed against human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2. |
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1229208-44-9 |
Entospletinib (GS-9973) |
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GS-9973 is a highly selective and orally efficacious Syk inhibitor(IC50= 7.7 nM) which is currently undergoing clinical evaluation for autoimmune and oncology indications. |
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