CAS NO. |
Products Name |
1216665-49-4 |
APY29 |
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APY29 are IRE1 allosteric modulators of Alpha, IRE1-Alpha phosphorylation, the IC50 for 280 nM, activated IRE1-Alpha activity of RNase. |
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960203-27-4 |
Vortioxetine (Lu AA21004) |
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Vortioxetine (Lu AA21004) is a multimodal serotonergic agent, inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT with IC50 of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively. |
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1238697-26-1 |
TAK-063 |
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TAK-063 is a selective PDE10A efficient inhibitors, an orally active, PDE10A IC50 values for 0.3nM, no effects on other PDEs. |
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1000998-59-3 |
BMS-687453 |
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BMS-687453 is an effective and selective PPAR-Alpha agonist, on human PPAR-α, the EC50 for 10 nM, 410 times times higher than on human selective PPAR gamma. |
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1448671-31-5 |
AZD3965 |
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AZD3965 is a potent, selective and orally available monocarboxylate transporter 1 (MCT1) inhibitor with a binding affinity of 1.6 nM, 6-fold selective over MCT2. |
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