CAS NO. |
Products Name |
|
403811-55-2 |
10058-F4 |
more... |
10058-F4 is a cell-permeable thiazolidinone that specificallly inhibits the c-Myc-Max interaction and prevents transactivation of c-Myc target gene expression; induces cell-cycle arrest and apoptosis. |
|
802904-66-1 |
AZD1981 |
more... |
AZD1981 is a potent and selective CRTh2 antagonist; displaces radio-labelled PGD2 from human recombinant DP2 with high potency (pIC50 = 8.4). |
|
894187-61-2 |
STF-118804 |
more... |
STF-118804 is a highly specific NAMPT inhibitor; reduces the viability of most B-ALL cell lines with IC50 <10 nM. |
|
939055-18-2 |
FIPI |
more... |
FIPI is a derivative of halopemide which potently inhibits both PLD1 (IC50 = 25 nM) and PLD2 (IC50 = 20 nM); prevents PLD regulation of F-actin cytoskeleton reorganization, cell spreading, and chemotaxis. |
|
348575-88-2 |
Optovin |
more... |
Optovin is a reversible photoactive TRPA1 activator; stimulates human TRPA1 channels in vitro and enables repeated photoactivation of motor behaviors in wild-type zebrafish (EC50 = 2 μM). |
|
22978-25-2 |
GW9662 |
more... |
GW9662 is a selective PPAR antagonist for PPARγ with IC50 of 3.3 nM, with ~10 and ~1000-fold functional selectivity in cells against PPARα and PPARδ, respectively. |
|
1253452-78-6 |
KS176 |
more... |
KS176 is a potent and selective inhibitor of the breast cancer resistance protein (BCRP) multidrug transporter (IC50 values are 0.59 and 1.39 μM in Pheo A and Hoechst 33342 assays respectively). Displays no inhibitory activity against P-gp or MRP1. |
|
313516-66-4 |
T0070907 |
more... |
T0070907 is a potent and selective PPARγ antagonist with IC50 of 1 nM; displays > 800-fold selectivity for PPARγ over PPARα and PPARδ. |
|
312756-74-4 |
RS1 |
more... |
RS-1 is a RAD51-stimulatory compound, which increases the DNA binding activity of RAD51. It is reported that RS-1 can be used to kill human cancer cells, and that its toxicity is modulated by both RAD51 and RAD54 translocase expression levels |
|
178946-89-9 |
C-DIM12 |
more... |
C-DIM12 is a synthetic Nurr1 activaor induces Nurr1 and DA gene expression in cell lines and primary neurons. |
|
1161233-85-7 |
BTZ043 |
more... |
BTZ043 is a inhibitor of decaprenyl-phosphoribose-epimerase (DprE1), It can display nanomolar bactericidal activity against Mycobacterium tuberculosis in vitro. |
|