CAS NO. |
Products Name |
1448428-04-3 |
Selonsertib |
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GS-4997 is a highly selective and potent once-daily oral ASK1 inhibitor that competes with ATP in the ASK1 catalytic kinase domain. |
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1346547-00-9 |
GSK583 |
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GSK583 is a highly potent and selective inhibitor of RIP2 Kinase. RIP2 kinase is a central component of the innate immune system and enables downstream signaling following activation of the pattern recognition receptors NOD1 and NOD2, leading to the production of inflammatory cytokines. |
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1445993-26-9 |
Mivebresib |
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Mivebresib, a novel BET family inhibitor, disrupts critical transcription programs that drive prostate cancer growth to induce potent anti-tumor activity in vitro and in vivo. Also a potent inhibitor of MYC and the TMPRSS2-ETS fusion proteins |
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1332708-14-1 |
PF-4840154 |
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PF-4840154 is a potent, selective agonist of the rat and human TrpA1 channel and elicited TrpA1-mediated nocifensive behaviour in mouse, with EC50 of 97 nM and 23 nM for rTrpA1 and hTrpA1, respectively. |
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315702-99-9 |
STF-62247 |
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STF-62247 is TGN inhibitor with IC50 of 0.625μM and 16μM in RCC4 and RCC4/VHL cells,respectively.It specifically induces autophagic cell death in cells that have lost VHL, an essential mutation in the development of RCC. |
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1235481-90-9 |
P7C3-A20 |
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P7C3-A20 is an analogue of P7C3, and is a proneurogenic, neuroprotective agent. P7C3-A20 exerted an antidepressant-like effect in wild-type littermates than P7C3. display increased activity and an improved toxicity profile compared to P7C3. P7C3 is a NAMPT activator. |
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292632-98-5 |
L-685458 |
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L-685458 is a potent inhibitor of Amyloid β-Protein precursor γ-secretase activity with IC50 of 17 nM, shows greater than 50-100-fold selectivity over other aspartyl proteases tested. |
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899713-86-1 |
ML348 |
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ML348 is a selective and reversible lysophospholipase 1 (LYPLA1) inhibitor (IC50 = 210 nM), Exhibits 14-fold selectivity for LYPLA1 over LYPLA2, Also selective over a panel of ~30 other serine hydrolases. |
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41332-24-5 |
NP118809 |
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NP-118809(39-1B4) is a potent N-type calcium channel blockers(IC50= 0.11 uM) ; good selectivity over L-type calcium channels. |
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204656-20-2 |
Liraglutide |
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Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus. |
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646502-53-6 |
VCMMAE |
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VcMMAE is a valuable reagent used for compound synthesis and modification, with no toxicity and harmfulness for human health. VcMMAE can be used conveniently in R&D. |
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