CAS NO. |
Products Name |
439081-18-2 |
Afatinib (BIBW2992) |
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Afatinib (BIBW2992) irreversibly inhibits EGFR/HER2 including EGFR(wt), EGFR(L858R), EGFR(L858R/T790M) and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM in cell-free assays, respectively; 100-fold more active against Gefitinib-resistant L858R-T790M EGFR mutant. |
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292632-98-5 |
L-685458 |
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L-685458 is a potent inhibitor of Amyloid β-Protein precursor γ-secretase activity with IC50 of 17 nM, shows greater than 50-100-fold selectivity over other aspartyl proteases tested. |
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61350-00-3 |
VU0364770 |
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VU0364770 is an allosteric of metabotropic glutamate receptor 4 (mGlu4) modulator, which exhibits a EC50 of 1.1±0.2 μM at human mGlu4. |
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433967-28-3 |
VU0357121 |
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VU0357121 is a novel positive and highly selective allosteric modulator (PAM) of mGlu5R with EC50 of 33 nM. |
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899713-86-1 |
ML348 |
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ML348 is a selective and reversible lysophospholipase 1 (LYPLA1) inhibitor (IC50 = 210 nM), Exhibits 14-fold selectivity for LYPLA1 over LYPLA2, Also selective over a panel of ~30 other serine hydrolases. |
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41332-24-5 |
NP118809 |
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NP-118809(39-1B4) is a potent N-type calcium channel blockers(IC50= 0.11 uM) ; good selectivity over L-type calcium channels. |
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204656-20-2 |
Liraglutide |
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Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus. |
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646502-53-6 |
VCMMAE |
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VcMMAE is a valuable reagent used for compound synthesis and modification, with no toxicity and harmfulness for human health. VcMMAE can be used conveniently in R&D. |
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