| CAS NO. |
Products Name |
|
|
| 209984-57-6 |
LY411575 |
more... |
| LY411575 is a potent γ-secretase inhibitor with IC50 of 0.078 nM/0.082 nM (membrane/cell-based), also inhibits Notch clevage with withIC50 of 0.39 nM |
|
| 471905-41-6 |
MK-0752 |
more... |
| MK-0752 is a moderately potent γ-secretase inhibitor, which reduces Aβ40 production with IC50 of 5 nM. Phase 1/2. |
|
| 1226056-71-8 |
Thiazovivin |
more... |
| Thiazovivin (Tzv) is a novel ROCK inhibitor with IC50 of 0.5 μM, promotes hESC survival after single-cell dissociation |
|
| 129830-38-2 |
Y27632 2hcl |
more... |
| Y-27632 2HCl is a selective ROCK1 (p160ROCK) inhibitor with Ki of 140 nM, exhibits >200-fold selectivity over other kinases, including PKC, cAMP-dependent protein kinase, MLCK and PAK. |
|
| 1342278-01-6 |
RKI-1447 |
more... |
| RKI-1447 is a potent inhibitor of ROCK1 and ROCK2, with IC50 of 14.5 nM and 6.2 nM, respectively, has anti-invasive and antitumor activities. |
|
| 850664-21-0 |
GSK269962A(GSK269962) |
more... |
| GSK269962A(GSK269962) is a potent ROCK inhibitor (IC50 values are 1.6 and 4 nM for recombinant human ROCK1 and ROCK2 respectively); displays greater than 30-fold selectivity for ROCK against a panel of serine/threonine kinases. |
|
|
|
| 105628-07-7 |
Fasudil hydrochloride |
more... |
| Fasudil Hcl(HA-1077; AT-877) is a potent inhibitor of ROCK-II, PKA, PKG, PKC, and MLCK with Ki of 0.33 μM, 1.6 μM, 1.6 μM, 3.3 μM and 36 μM, respectively. |
|
| 105628-07-7 |
Fasudil (HA-1077) HCl |
more... |
| Fasudil (HA-1077) HCl is a potent inhibitor of ROCK-II, PKA, PKG, PKC, and MLCK with Ki of 0.33 μM, 1.6 μM, 1.6 μM, 3.3 μM and 36 μM in cell-free assays, respectively. |
|
|
|
| 120685-11-2 |
PKC412(Midostaurin; CGP41231; CGP41251) |
more... |
| PKC412(Midostaurin; CGP41231; CGP41251) is a broad-spectrum protein kinase inhibitor that can inhibit PKC-α, β), gamma, PDFR Beta), VEGFR2, Syk, PKC η, Flk-1, Flt3, Cdk1/B, PKA, c-Kit, c-Fgr, c-Src, VEGFR1 and EGFR. |
|
All Products
