| CAS NO. |
Products Name |
| 667463-62-9 |
BIO |
more... |
| BIO (6-bromoindirubin-3'-oxime) is a specific inhibitor of GSK-3 with IC50 of 5 nM for GSK-3α/β, shows >16-fold selectivity over CDK5, also a pan-JAK inhibitor |
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| 252917-06-9 |
CHIR-99021 (CT99021) HCl |
more... |
| CHIR-99021 HCl (CT99021) is hydrochloride of CHIR-99021, which is a GSK-3α/β inhibitor with IC50 of 10 nM/6.7 nM; ability to distinguish between GSK-3 and its closest homologs Cdc2 and ERK2 |
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| AZD2858 |
AZD2858 |
more... |
| AZD2858 is a selective GSK-3 inhibitor with an IC50 of 68 nM, activating Wnt signaling, increases bone mass in rats |
|
| 702675-74-9 |
BX-795 |
more... |
| BX795 is a potent and specific PDK1 inhibitor with IC50 of 6 nM, 140- and 1600-fold more selective for PDK1 than PKA and PKC, respectively. Meanwhile, in comparison to GSK3β more than 100-fold selectivity observed for PDK1. |
|
| 702674-56-4 |
BX-912 |
more... |
| BX-912 is a potent and specific PDK1 inhibitor with IC50 of 12 nM, 9- and 105- fold greater selectivity for PDK1 than PKA and PKC, respectively. In comparison to GSK3β, selectivity for PDK1 is 600-fold. |
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| 1180676-32-7 |
PS48 |
more... |
| PDK1 PS48 is a small molecule agonists and Kd value is 10.3uM, the specificity of PDK1 PIF-binding of pocket, different from the ATP binding site. |
|
| 1233533-04-4 |
kb NB 142-70 |
more... |
| kb NB 142-70 is a selective protein kinase D (PKD) inhibitor (IC50 values are 28.3, 58.7 and 53.2 nM for PKD1, 2 and 3 respectively). |
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