| CAS NO. |
Products Name |
| 808118-40-3 |
FG-4592 |
more... |
| FG-4592 is an HIF α prolyl hydroxylase inhibitor, stabilizes HIF-2 and induces EPO production. Phase 3. |
|
| 931398-72-0 |
IOX2 |
more... |
| IOX2 is a potent inhibitor of HIF-1α prolyl hydroxylase-2 (PHD2) with IC50 of 21 nM, >100-fold selectivity over JMJD2A, JMJD2C, JMJD2E, JMJD3, or the 2OG oxygenase FIH. |
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| 1154028-82-6 |
Molidustat (BAY85-3934) |
more... |
| Molidustat(BAY-85-3934) is a novel inhibitor of hypoxia-inducible factor (HIF) prolyl hydroxylase (PH) which stimulates erythropoietin (EPO) production and the formation of red blood cells; HIF-stabilizer. |
|
| 223387-75-5 |
FG-2216 |
more... |
| FG-2216 is a potent HIF-prolyl hydroxylase inhibitor with IC50 of 3.9 uM for PDH2 enzyme; orally bioavailable and induced significant and reversible Epo induction in vivo. |
|
| 1193383-09-3 |
JNJ-42041935 |
more... |
| JNJ-42041935 is a potent (pKi = 7.3-7.9), 2-oxoglutarate competitive, reversible, and selective inhibitor of PHD enzymes. |
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|
| 1446790-62-0 |
RO0921 |
more... |
| RO9021 is an orally bioavailable, novel ATP-competitive inhibitor of SYK, with an average IC50 of 5.6 nM. |
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