| CAS NO. |
Products Name |
| 1118807-13-8 |
KY02111 |
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| KY02111 promotes differentiation of hPSCs to cardiomyocytes by inhibiting Wnt signaling, may act downstream of APC and GSK3β. |
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| 1243243-89-1 |
Wnt-c59 |
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| Wnt-C59 (C59) is a PORCN inhibitor for Wnt3A-mediated activation of a multimerized TCF-binding site driving luciferase with IC50 of 74 pM. |
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| 1127442-82-3 |
IWR-1-endo |
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| IWR-1-endo is a Wnt pathway inhibitor with IC50 of 180 nM, induces Axin2 protein levels and promotes β-catenin phosphorylation by stabilizing Axin-scaffolded destruction complexes. |
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| 1123231-07-1 |
WAY-262611 |
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| WAY-262611 is a wingless β-Catenin agonist that increases bone formation rate; with EC50 of 0.63 uM in TCF-Luciferase assay. |
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| 950912-80-8 |
PF670462 |
more... |
| PF-670462 is a potent (IC50 = 7.7 ± 2.2 nM) and selective (>30-fold with respect to 42 additional kinases) inhibitor of CK1ε in isolated enzyme preparations. |
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| 1638250-96-0 |
ETC-159 |
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| ETC-159 is a potent and specific inhibitor of Wnt secretion. ETC-159 inhibits β-catenin reporter activity in a dose-dependent manner with an IC50 of 2.9 nM. |
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| 186611-52-9 |
SU-5607 |
more... |
| IC261 is a novel inhibitor of CK1, triggers the mitotic checkpoint control. The IC50 of IC261 for CK1 was 16 μM and for Cdk5 is 4.5 mM. |
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| 1243244-14-5 |
LGK974 |
more... |
| LGK-974 is a potent and specific PORCN inhibitor, and inhibits Wnt signaling with IC50 of 0.4 nM. |
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XMU-MP-1 |
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| XMU-MP-1 is a reversible and selective MST1/2 inhibitor with IC50 values of 71.1 ± 12.9 nM and 38.1 ± 6.9 nM against MST1 and MST2, respectively. XMU-MP-1 also reduces the phosphorylation of LATS1/2, and YAP by inhibiting MST1/2 kinase activities. |
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