CAS NO. |
Products Name |
1262888-28-7 |
Spautin-1 |
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Spautin-1 is a novel autophagy inhibitor, IM inhibited the growth of K562 cells with IC50 of 1.03 μM. In contrast, co-treatment with Spautin-1 increased IM-induced inhibition of cell viability with IC50 of 0.45 μM. |
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353262-04-1 |
NS6180 |
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NS6180 is a novel potent and selective KCa3.1 channel inhibitor(IC50= 9 nM) prevents T-cell activation and inflammation |
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1134156-31-2 |
VER155008 |
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VER-155008 is a potent Hsp70 family inhibitor with IC50 of 0.5 μM, 2.6 μM, and 2.6 μM in cell-free assays for HSP70, HSC70, and GRP78, respectively, >100-fold selectivity over HSP90. |
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19542-67-7 |
BAY11-7082 |
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BAY 11-7082 is a NF-κB inhibitor, inhibits TNFα-induced IκBα phosphorylation with IC50 of 10 μM in tumor cells. Also inhibiting components of the ubiquitin system. |
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1508250-71-2 |
EGF816 |
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EGF816 is a novel covalent inhibitor of mutant-selective EGFR; overcomes T790M-mediated resistance in NSCLC. |
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1108743-60-7 |
Entrectinib |
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Entrectinib(NMS-E628、RXDX-101) is an orally available ALK inhibitor; exhibits good activity against NPM–ALK with an IC50 value of 55 nM. |
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1613028-81-1 |
SR9243 |
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SR9243 is a LXR inverse agonist that induces LXR-corepressor interaction; shows anticancer activity and selectively targets the warburg effect and lipogenesis. |
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142273-20-9 |
Kenpaullone |
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Kenpaullone is an ATP-competitive inhibitor of several CDKs (cyclin-dependent kinases) as well as GSK-3β (glycogen synthase kinase 3β). |
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181632-25-7 |
SB242084 |
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SB 242084 is a 5-HT2C receptor antagonist(pKi=9.0) that displays 158- and 100-fold selectivity over 5-HT2A and 5-HT2B receptors respectively. |
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