| CAS NO. |
Products Name |
| 2274819-46-2 |
LUT-014 |
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| LUT014 is a B-Raf inhibitor with an IC50 of 11.7 nM, and developed to reduce dose-limiting acneiform lesions associated EGFR Inhibitors treatment. Extracted from patent WO 2019026065A2 |
|
| 1234479-76-5 |
ERK5-IN-1 |
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| ERK5-IN-1 is a potent ERK5 inhibitor with an IC50 of 87±7 nM. ERK5-IN-1 also inhibits LRRK2[G2019S] with an IC50 of 26 nM. |
|
| 2093393-05-4 |
TC13172 |
more... |
| TC13172 is a mixed lineage kinase domain-like protein (MLKL) inhibitor with an EC50 value of 2 nM for HT-29 cells. |
|
| 1207293-36-4 |
BI-847325 |
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| BI-847325 is an ATP competitive dual inhibitor of MEK and aurora kinases (AK) with IC50 values of 4 and 15 nM for human MEK2 and AK-C, respectively. |
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|
| 1315355-93-1 |
NG25 |
more... |
| NG25 is a potent dual TAK1 and MAP4K2 inhibitor, with IC50s of 149 nM and 21.7 nM, respectively. |
|
| 1184173-73-6 |
MK8353 |
more... |
| MK-8353 (SCH900353) is a potent, selective and orally available ERK1/2 inhibitor, with IC50s of 23.0 nM and 8.8 nM, respectively; MK-8353 has antitumor activity. |
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