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Home  All Products |
| All Products >>Cell Cycle/DNA Damage |
| CAS NO. |
Products Name |
| 1816989-16-8 |
SY-1365 |
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| SY-1365 is a highly selective covalent inhibitor of CDK7. SY-1365 possesses therapeutic potential in both hematological and solid tumors[ |
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| 879127-16-9 |
Aurora Kinase Inhibitor 3 |
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| Aurora Kinase Inhibitor 3 is a strong and selective Aurora A kinase inhibitor with an IC50 of 42 nM, and weakly inhibits EGFR with an IC50>10 μM. Aurora Kinase Inhibitor 3 has a binding mode with the cyclopropanecarboxylic acid moiety directed towards the solvent exposed region of the ATP-binding pocket, and several induced structural changes in the active-site compared with other published AIK structures |
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| 1228013-15-7 |
CC115 |
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| CC-115 is a potent and dual DNA-PK and mTOR kinase inhibitor with IC50s of 13 nM and 21 nM, respectively. CC-115 blocks both mTORC1 and mTORC2 signaling. |
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