| CAS NO. |
Products Name |
| 1228013-30-6 |
CC-223 |
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| CC-223 is a potent mTOR kinase inhibitor (IC50=16 nM), with >150-fold sensitivity over the related lipid kinase PI3Kα (IC50=4 μM). |
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| 900185-01-5 |
PIK-293 |
more... |
| PIK-293 is a $literal inhibitor, the most effective roles in PI3K Delta, IC50 0.24, for PI3K alpha / beta / gamma effect low of 500,100 and 50 times times respectively. |
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| 307538-42-7 |
SMER28 |
more... |
| SMER28 is a small molecule modulator of autophagy acting via an mTOR-independent mechanism, prevented the accumulation of amyloid beta peptide. an activator of autophagy. |
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| 1613724-42-7 |
HTH-01-015 |
more... |
| HTH-01-015 is a potent and selective inhibitor of NUAK1 with IC50 of 100 nM, does not significantly inhibit NUAK2 (IC50 of >10 μM). |
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| 1382979-44-3 |
GDC0084 |
more... |
| GDC-0084 is a potent, selective inhibitor of Class I PI3K and mTOR with good penetration across the blood-brain barrier. |
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| 844499-71-4 |
A-769662 |
more... |
| A-769662 is a potent, reversible AMPK activator with EC50 of 0.8 μM, little effect on GPPase/FBPase activity. |
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| 1532533-67-7 |
TGR1202 |
more... |
| TGR-1202 is an orally available, next generation PI3Kdelta inhibitor, inhibits PI3Kδ activity in enzyme and cell based assays with IC50 and EC50 values of 22.2 and 24.3 nM respectively. |
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| 1214265-58-3 |
WZ4003 |
more... |
| WZ4003 is a first potent and highly specific protein kinase inhibitor of NUAK kinases with IC50 of 20 nM/100 nM for NUAK1/NUAK2; no significant inhibition on 139 other kinases. |
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