| CAS NO. |
Products Name |
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| 1092499-93-8 |
NVP-BSK805 |
more... |
| NVP-BSK805 is a potent and selective ATP-competitive JAK2 inhibitor with IC50 of 0.5 nM; >20-fold selectivity towards JAK1, JAK3 and TYK2. |
|
| 457081-03-7 |
Pyridone 6 |
more... |
| Pyridone 6 are highly active JAK inhibitors of JAK1 (mice), JAK2 and Tyk2 IC50 15 1 nM and nM,1 nM, respectively, Ki of JAK3 is 5 nM, very low affinity to other protein tyrosine kinase. |
|
| 936091-14-4 |
TG101209 |
more... |
| TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM, less potent to Flt3 and RET with IC50 of 25 nM and 17 nM in cell-free assays, ~30-fold selective for JAK2 than JAK3, sensitive to JAK2V617F and MPLW515L/K mutations. |
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| 1092499-93-8 |
NVP-BSK805 2HCl |
more... |
| NVP-BSK805 2HCl is a potent and selective ATP-competitive JAK2 inhibitor with IC50 of 0.5 nM,>20-fold selectivity towards JAK1, JAK3 and TYK2 |
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| 1206163-45-2 |
Solcitinib |
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| Solcitinib is a selective Janus kinase 1 (JAK1) inhibitor, for the treatment of psoriasis, lupus, and ulcerative colitis. |
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| 1271022-90-2 |
BMS911543 |
more... |
| BMS-911543 is a potent and selective small-molecule inhibitor of JAK2, displays potent anti-proliferative and pharmacodynamic (PD) effects in cell lines dependent upon JAK2 signaling. |
|
| 944118-01-8 |
Peficitinib |
more... |
| Peficitinb (ASP015K, JNJ-54781532) is a novel oral Janus kinase (JAK) inhibitor. Peficitinib inhibits JAK1, JAK2, JAK3 and Tyk2 enzyme activities with IC50s of 3.9, 5.0, 0.71 and 4.8 nM, respectively, and has moderate selectivity for JAK3 inhibition. |
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