| CAS NO. |
Products Name |
| 1173097-76-1 |
U0126-EtOH |
more... |
| U0126-EtOH(U-0126) is a highly selective inhibitor of MEK1/2 with IC50 of 0.07 μM/0.06 μM, 100-fold higher affinity for ΔN3-S218E/S222D MEK than PD098059. |
|
| 923032-37-5 |
Refametinib（RDEA119) |
more... |
| Refametinib (RDEA119, BAY 86-9766), is an orally bioavailable selective MEK inhibitor with potential antineoplastic activity (IC50=19 nM MEK1; IC50=47 nM MEK2). |
|
|
|
| 271576-80-8 |
SD-06 |
more... |
| SD-06 is a p38 MAP kinase inhibitor; inhibits p38α with an IC50 value of 170 nM and inhibits LPS-stimulated TNF-release in rats (83% inhibition at 1mg/kg, po). |
|
| 1628838-42-5 |
RAF709 |
more... |
| RAF709 is a novel Raf kinase inhibitor extracted from patent WO2014151616A1, compound example 131, has an IC50 of 0.5 and 1.8 nM for c-Raf and b-Raf, respectively |
|
| 1951483-29-6 |
LY3214996 |
more... |
| LY3214996 is a highly selective inhibitor of ERK1 and ERK2, with IC50 of 5 nM for both enzymes in biochemical assays. |
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