| CAS NO. |
Products Name |
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| 950762-95-5 |
PCI-34051 |
more... |
| PCI-34051 is a potent and specific HDAC8 inhibitor with IC50 of 10 nM in a cell-free assay. It has greater than 200-fold selectivity over HDAC1 and 6, more than 1000-fold selectivity over HDAC2, 3, and 10. |
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| 875320-29-9 |
Quisinostat (JNJ-26481585) |
more... |
| Quisinostat is an orally available, potent, hydroxamate, pan-HDACi with broad activity in solid and hematologic tumor models. Quisinostat inhibits HDAC1 (IC50 = 0.11 nM), HDAC2 (IC50 = 0.33 nM), HDAC4 (IC50 = 0.64 nM), HDAC10 (IC50 = 0.46 nM), HDAC11 (IC50 = 0.37 nM). |
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| 1375465-91-0 |
ACY738 |
more... |
| ACY-738 demonstrates inhibitory activity against recombinant HDAC6 with IC50 values of 1.7 nM, with respective average selectivity over class I HDACs being 100-fold. |
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