| CAS NO. |
Products Name |
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| 1152311-62-0 |
VX661 |
more... |
| VX-661 is a second F508del CFTR corrector and is believed to help CFTR protein reach the cell surface. Phase 2. |
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| 957217-65-1 |
BTZ043 Racemate |
more... |
| BTZ043 racemate is a decaprenylphosphoryl-β-D-ribose 2'-epimerase (DprE1) inhibitor acting as a new antimycobacterial agent that kill Mycobacterium tuberculosis. |
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| 875446-37-0 |
Anacetrapib (MK-0859) |
more... |
| Anacetrapib (MK0859) is a potent, selective, reversible rhCETP and mutant CETP(C13S) inhibitor with IC50 of 7.9 nM and 11.8 nM, increases HDL-C and decreases LDL-C, does not increase aldosterone or blood pressure. Phase 3. |
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| 1202757-89-8 |
AVL292 |
more... |
| AVL-292 is a covalent, orally active, and highly selective BTK inhibitor with IC50 of <0.5 nM, displaying at least 1400-fold selectivity over the other kinases assayed. Phase 1. |
|
| 1124329-14-1 |
AZ3146 |
more... |
| AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM, contributes to recruitment of CENP-E (kinesin-related motor protein), less potent to FAK, JNK1, JNK2, and Kit. |
|
| 848141-11-7 |
Avelestat (AZD9668) |
more... |
| Avelestat (AZD9668) is an oral, highly selective inhibitor of neutrophil elastase (NE) with IC50 and Ki of 12 nM and 9.4 nM, at least 600-fold more selective over other serine proteases. Phase 2. |
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