| CAS NO. |
Products Name |
| 864821-90-9 |
Eluxadolin |
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| Eluxadoline(JNJ-27018966) is an orally active mixed μ opioid receptor (μOR) agonist δ opioid receptor (δOR) antagonist. |
|
| 223488-57-1 |
CP533536 |
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| Evatanepag (CP-533536) is an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation with EC50 of 0.3 nM. |
|
| 1135242-13-5 |
VU0357017 hydrochloride |
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| VU0357017 hydrochloride is a highly selective M1 agonists that appear to act at an allosteric site to activate the receptor (EC50 = 477 ± 172 nM; pEC50 = 6.37 ± 0.15). |
|
| 1161205-04-4 |
VU0361737 |
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| VU 0361737 is a selective positive allosteric modulator (PAM) for mGlu4 receptor with EC50 of 240 nM and 110 nM at human and rat receptors, respectively, displays weak activity at mGlu5 and mGlu8 receptors, is inactive at mGlu1, mGlu2, mGlu3, mGlu6 and mGlu7 receptors. |
|
| 259869-55-1 |
JWH-133 |
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| JWH 133 is a potent CB2 selective agonist with Ki of 3.4 nM, 200-fold selective over CB1 receptors. |
|
| 1637739-82-2 |
BQU57 |
more... |
| BQU57 shows selective inhibition for Ral relative to Ras or Rho and inhibit xenograft tumor growth similar to depletion of Ral by siRNA. The IC50 for BQU57 of 2.0 μM in H2122 and 1.3 μM in H358. |
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|
| 406205-74-1 |
BAY59-3074 |
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| Bay 59-3074 is a novel, selective CB1/CB2 receptor partial agonist with Ki values of 48.3 and 45.5 nM at human CB1 and CB2 receptors respectively . Orally active CB1 agonist in vivo. |
|
| 159182-43-1 |
L755507 |
more... |
| L-755,507 is characterized as a potent and selective β3 adrenergic receptor partial agonist with EC50 of 0.43 nM. It is also recently identified to enhance CRISPR-mediated homology-directed repair (HDR) efficiency in human induced pluripotent stem cells (iPSCs) and other cell types. |
|
| 733767-34-5 |
NSC23766 |
more... |
| NSC 23766 is a specific inhibitor of the binding and activation of RAC GTPase with IC50 of ~50 μM; does not inhibit the closely related targets, Cdc42 or RhoA. |
|
| 165377-44-6 |
SA-4503 |
more... |
| SA4503 2Hcl(AGY-94806 2Hcl; Cutamesine 2Hcl) is a selective sigma 1 receptor(σ1R) agonist; high affinity for the sigma 1 receptor subtype labeled by (+)-[3H]pentazocine (IC50 = 17.4 +/- 1.9 nM); 100-fold less affinity for the sigma 2 receptor. |
|
| 754240-09-0 |
EHT1864 |
more... |
| EHT 1864 is a small molecule inhibitor of Rac1 signaling; modulate γ-Secretase-mediated APP processing. |
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