| CAS NO. |
Products Name |
| 733767-34-5 |
NSC23766 |
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| NSC 23766 is a specific inhibitor of the binding and activation of RAC GTPase with IC50 of ~50 μM; does not inhibit the closely related targets, Cdc42 or RhoA. |
|
| 1243244-14-5 |
LGK974 |
more... |
| LGK-974 is a potent and specific PORCN inhibitor, and inhibits Wnt signaling with IC50 of 0.4 nM. |
|
| 1035227-43-0 |
AZ505 |
more... |
| AZ505 is a potent and highly selective inhibitor of the oncogenic protein SMYD2(IC50=0.12 uM) with potential anticancer activity, >600 fold than SMYD3(IC50>83.3 uM); DOT1L(IC50>83.3 uM);EZH2(IC50>83.3 uM). |
|
| 1818885-28-7 |
ARV-825 |
more... |
| ARV-825 is a BRD4 inhibitor with DC50 (50% of maximum degradation) ＜1nM for Burkitt's lymphoma (BL) cell lines. Affinity to BD1 and BD2 of BRD4 by ARV-825 is 90 and 28 nM, respectively. |
|
| 376348-65-1 |
Maraviroc |
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| Maraviroc (UK-427857; Selzentry; Celsentri) is a selective CCR5 antagonist (IC50= 6.4 nM); displays potent anti-HIV-1 activity. |
|
| 521984-48-5 |
SIS3 |
more... |
| SIS3 is a potent and selective inhibitor of Smad3. a potent regulator of the human Nox4 promoter. |
|
| 1125758-85-1 |
A804598 |
more... |
| A-804598 is a novel, competitive, and selective P2X7 receptor antagonist with IC50 of 10 nM, 9 nM and 11 nM in rat, mouse and human P2X7 receptors respectively. |
|
| 374913-63-0 |
Madrasin |
more... |
| Madrasin is a potent and cell penetrant splicing inhibitor that interferes with the early stages of spliceosome assembly. |
|
| 1224846-01-8 |
MK3697 |
more... |
| MK-3697 is an isonicotinamide small molecule, acting as a potent and selective Orexin 2 receptor antagonist with Ki = 0.95 nM. |
|
| 349085-38-7 |
HC-030031 |
more... |
| HC-030031 is a selective TRPA1 channel blocker that antagonizes AITC- and formalin-evoked calcium influx with IC50 of 6.2 μM and 5.3 μM respectively. |
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|
| 171500-79-1 |
Dalbavancin HCL |
more... |
| Dalbavancin(BI-397; MDL-63397) is a semisynthetic lipoglycopeptide, has potent activity against Gram-positive bacteria(MIC50=0.06 mg/L; B. anthracis). |
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