| CAS NO. |
Products Name |
|
|
| 1146963-51-0 |
J147 |
more... |
| J147 is a broad spectrum neuroprotective phenyl hydrazide compound(EC50=60-115 nM) with significant neurotrophic properties related to the induction of brain-derived neurotrophic factor (BDNF). |
|
| 121584-18-7 |
Valspodar (PSC-833) |
more... |
| Valspodar(PSC833) is a P-glycoprotein (P-gp) inhibitor widely used in preclinical and clinical studies for overcoming multidrug resistance (MDR). |
|
| 210344-95-9 |
z-devd-fmk |
more... |
| Z-DEVD-FMK is a specific, irreversible Caspase-3 inhibitor, and also shows potent inhibition on caspase-6, caspase-7, caspase-8, and caspase-10. |
|
| 1538604-68-0 |
BLU-9931 |
more... |
| BLU-9931 is the first selective small molecule inhibitor of FGFR4 with IC50 of 3 nM; less potent for FGFR1/2/3(IC50> 150 nM). |
|
| 4449-51-8 |
Cyclopamine |
more... |
| Cyclopamine(11-Deoxojervine) is a specific Hedgehog (Hh) signaling pathway antagonist of Smoothened (Smo) with IC50 of 46 nM. |
|
|
|
| 303727-31-3 |
L-779450 |
more... |
| L-779450 is a potent, ATP-competitive Raf kinase inhibitor (IC50 =10 nM) that displays > 7, > 30 and > 70-fold selectivity over p38α, GSK3β and Lck respectively. |
|
| 873786-09-5 |
PLX647 |
more... |
| PLX647 is a highly specific dual FMS/KIT kinase inhibitor with IC50 of 28/16 nM respectively. |
|
|
|
| 761437-28-9 |
NVP-TAE226 |
more... |
| NVP-TAE226 is a potent FAK inhibitor with IC50 of 5.5 nM and modestly potent to Pyk2(IC50=3.5 nM); 10- to 100-fold less potent against InsR, IGF-1R, ALK, and c-Met |
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